Christian Machens

Theoretical Neuroscience Lab

Champalimaud Neuroscience Programme

Welcome!

“In every special doctrine of nature only so much science proper can be found as there is mathematics in it" - Immanuel Kant (1724-1804)


How do the millions of neurons inside the brain coordinate their activity to make sense of the world and create behavior? This question stands at the center of our research. A lot of experimental labs address the question by measuring the behavior of animals, the electrical activity of neurons, the anatomical details of neural connectivity and so on. Our aim is to put order into these observations using the language of mathematics. More specifically, we develop methods to visualize and interpret neural recordings, we form theories of the computations implemented by neural circuits, and we construct models of the mechanisms underlying the computations. Many of the methods we apply are taken from physics, computer science, and engineering.

We are part of the Champalimaud Neuroscience Programme in Lisbon, Portugal, and have close ties with the Group for Neural Theory in Paris, France.

People

Christian Machens

Christian Machens

Principal Investigator


David Barrett

David Barrett

Post-Doc


Wieland Brendel

Wieland Brendel

PhD Student


Florian Dehmelt

Florian Dehmelt

PhD Student


Dmitry Kobak

Dmitry Kobak

Post-Doc


Nuno Calaim

Nuno Calaim

PhD Student


João Semedo

João Semedo

PhD Student


Alumni

Pedro Gonçalves

Pedro Gonçalves

PhD Student


Adrien Wohrer

Adrien Wohrer

Post-Doc (GNT, Paris)


Recent Publications

Disentangling the functional consequences of the connectivity between optic-flow processing neurons.

pdf download link to original
Weber F, Machens CK, Borst A (2012), Nature Neuroscience, in press.
pdf download

Demixed principal component analysis.

Brendel W , Romo R , Machens CK (2011), Advances in Neural Information Processing Systems 24.
pdf download

Linear readout from a neural population with partial correlation data.

Wohrer A , Romo R , Machens CK (2010), Advances in Neural Information Processing Systems 23.
pdf download link to original

Spatio-temporal response properties of optic-flow processing neurons.

Weber F , Machens CK , Borst A (2010), Neuron 67:628-641.
pdf download link to original

Demixing population activity in higher cortical areas.

Machens CK (2010), Frontiers in Computational Neuroscience 4(126).

A comprehensive list of publications can be found here.

How to find us

Machens Lab
Neurociências (26.34)
Centro Champalimaud – Champalimaud Centre for the Unknown
Av. Brasília, Doca de Pedrouços
1400-038 Lisboa, Portugal



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